|
|
4-Guanidinobutyrate + H2O <=> 4-aminobutanoate + Urea
|
3.5.3.10
D-arginase
3.5.3.17
guanidinopropionase
3.5.3.2
guanidinoacetase
3.5.3.7
guanidinobutyrase
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR22731
KEGG:
R01990
MetaCyc:
GUANIDINOBUTYRASE-RXN
SABIO-RK:
2030
|
|
|
|
H+ + L-glutamate <=> CO2 + 4-aminobutanoate
|
4.1.1.15
glutamate decarboxylase
4.1.1.25
tyrosine decarboxylase
4.1.1.29
sulfinoalanine decarboxylase
|
–
–
–
|
BMK
|
|
BRENDA:
BR275
KEGG:
R00261
MetaCyc:
GLUTDECARBOX-RXN
SABIO-RK:
766
|
|
|
|
4-Aminobutyraldehyde + NAD+ + H2O <=> 4-aminobutanoate + NADH + H+
|
1.2.1
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.47
4-trimethylammoniobutyraldehyde dehydrogenase
1.2.1.54
gamma-guanidinobutyraldehyde dehydrogenase
1.2.1.8
betaine-aldehyde dehydrogenase
|
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR29390
KEGG:
R02549
MetaCyc:
AMINOBUTDEHYDROG-RXN
SABIO-RK:
2464
|
|
|
|
4-acetamidobutanoate + H2O <=> 4-aminobutanoate + acetate
|
3.5.1.63
4-acetamidobutyrate deacetylase
|
–
|
MK
|
|
BRENDA:
BR29513
KEGG:
R01987
MetaCyc:
RXN-36
|
|
|
|
4-aminobutanoate + 2-oxoglutarate <=> succinate_semialdehyde + L-glutamate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.22
(S)-3-amino-2-methylpropionate transaminase
2.6.1.29
diamine transaminase
2.6.1.48
5-aminovalerate transaminase
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47437
KEGG:
R01648
MetaCyc:
GABATRANSAM-RXN
SABIO-RK:
1785
|
|
|
|
4-(glutamylamino)_butanoate + H2O <=> L-glutamate + 4-aminobutanoate
|
3.5.1.94
gamma-glutamyl-gamma-aminobutyrate hydrolase
|
–
|
BMK
|
|
BRENDA:
BR48700
KEGG:
R07419
MetaCyc:
RXN0-3942
|
|
|
|
4-methylaminobutanoate + O2 + H2O <=> 4-aminobutanoate + formaldehyde + H2O2
|
1.5.3.19
4-methylaminobutanoate oxidase (formaldehyde-forming)
|
–
|
MK
|
|
BRENDA:
BR50152
KEGG:
R10102
MetaCyc:
RXN-13067
|
|
|
|
4-aminobutanoate + pyruvate <=> succinate_semialdehyde + L-alanine
|
2.6.1.116
6-aminohexanoate aminotransferase
2.6.1.18
beta-alanine---pyruvate transaminase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.40
(R)-3-amino-2-methylpropionate---pyruvate transaminase
2.6.1.96
4-aminobutyrate---pyruvate transaminase
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR50304
KEGG:
R10178
MetaCyc:
RXN-6902
|
|
|
|
4-aminobutanoate + glyoxylate <=> succinate_semialdehyde + glycine
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.96
4-aminobutyrate---pyruvate transaminase
|
–
–
|
|
|
BRENDA:
BR50305
KEGG:
R10179
MetaCyc:
RXN-13328
|
|
|
|
4-aminobutanoyl-CoA + H2O <=> 4-aminobutanoate + CoA + H+
|
3.5.1.51
4-acetamidobutyryl-CoA deacetylase
|
–
|
|
|
BRENDA:
BS140555
MetaCyc:
RXN-21419
|
|
|
|
4-Aminobutyraldehyde + NADP+ + H2O <=> 4-aminobutanoate + NADPH + H+
|
1.2.1
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
|
–
–
–
|
K
|
|
BRENDA:
BS371909
KEGG:
R01986
MetaCyc:
RXN-14209
SABIO-RK:
2027
|
|
|
|
homocarnosine + H2O <=> 4-aminobutanoate + L-histidine
|
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.20
beta-Ala-His dipeptidase
3.4.13.5
Xaa-methyl-His dipeptidase
|
–
–
–
|
K
|
|
BRENDA:
BS382034
KEGG:
R01992
MetaCyc:
RXN-19944
SABIO-RK:
2032
|
|
|
|
4-aminobutanoate + L-histidine + ATP <=> H+ + homocarnosine + ADP + phosphate
|
6.3.2.11
carnosine synthase
|
–
|
MK
|
|
BRENDA:
BS404431
KEGG:
R01991
MetaCyc:
RXN-11222
|
|
|
|
DELTA1-pyrroline + NAD+ + H2O <=> 4-aminobutanoate + NADH + H+
|
1.2.1
1.2.1.19
aminobutyraldehyde dehydrogenase
|
–
–
|
|
|
BRENDA:
BS451438
MetaCyc:
1.5.1.35-RXN
SABIO-RK:
12834
|
|
|
|
L-arginine + 4-aminobutanoate <=> 4-Guanidinobutyrate + L-ornithine
|
2.1.4.1
glycine amidinotransferase
|
–
|
K
|
|
BRENDA:
BS320131
KEGG:
R01989
|
|
|
|
4-aminobutanoate + L-glutamate <=> L-glutamate + 4-aminobutanoate
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-261
|
|
|
|
H+ + 4-aminobutanoate <=> H+ + 4-aminobutanoate
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-57
|
|
|
|
4-aminobutanoate + O2 + H2O <=> succinate_semialdehyde + NH3 + H2O2
|
1.4.3.21
primary-amine oxidase
1.5.3.21
4-methylaminobutanoate oxidase (methylamine-forming)
|
–
–
|
|
|
BRENDA:
BS420028
|
|
|
|
4-aminobutyronitrile + H2O <=> 4-aminobutanoate + NH3
|
3.5.5.1
nitrilase
3.5.5.7
aliphatic nitrilase
|
–
–
|
|
|
BRENDA:
BS433272
|
|
|
|
4-aminobutanoate + 2-oxoglutarate + O2 <=> D-2-hydroxy-4-aminobutyric_acid + succinate + CO2
|
1.14.11.17
taurine dioxygenase
|
–
|
|
|
BRENDA:
BS440837
|
|
|
|
5''-phospho-pyridoxyl-4-aminobutyrate + H2O + O2 <=> pyridoxal_5''-phosphate + 4-aminobutanoate + H2O2
|
1.4.3.5
pyridoxal 5'-phosphate synthase
|
–
|
|
|
BRENDA:
BS259076
|
|
|
|
ITP + L-histidine + 4-aminobutanoate <=> IMP + phosphate + homocarnosine
|
6.3.2.11
carnosine synthase
|
–
|
|
|
BRENDA:
BS406
|
|
|
|
4-aminobutyramide + H2O <=> 4-aminobutanoate + NH3
|
3.5.1.30
5-aminopentanamidase
|
–
|
|
|
BRENDA:
BS116274
|
|
|
|
4-ureidobutyrate + H2O <=> 4-aminobutanoate + CO2 + NH3
|
3.5.1.6
beta-ureidopropionase
|
–
|
|
|
BRENDA:
BS116344
|
|
|
|
N2-(4-aminobutyryl)-L-lysine + H2O <=> 4-aminobutanoate + L-lysine
|
3.4.13.4
Xaa-Arg dipeptidase
|
–
|
|
|
BRENDA:
BS382396
|
|
|
|
4-aminobutanoate + 2-oxoglutarate <=> succinate_semialdehyde + D-glutamate
|
2.6.1.54
pyridoxamine-phosphate transaminase
|
–
|
|
|
BRENDA:
BS354481
|
|
|
|
4-aminobutanoate + 2-oxoglutarate <=> L-glutamate + acetaldehyde + sulfite
|
2.6.1.55
taurine---2-oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353592
|
|
|
|
4-aminobutanoate + Butyraldehyde <=> succinate_semialdehyde + n-butylamine
|
2.6.1.18
beta-alanine---pyruvate transaminase
|
–
|
|
|
BRENDA:
BS436898
|
|
|
|
4-aminobutanoate + 4,5-Dioxopentanoate <=> 5-aminolevulinate + succinate_semialdehyde
|
2.6.1.43
aminolevulinate transaminase
|
–
|
|
|
BRENDA:
BS356613
|
|
|
|
(R)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric_acid + H2O <=> 4-aminobutanoate + (R)-pantoate
|
3.5.1.22
pantothenase
|
–
|
|
|
BRENDA:
BS116223
|
|
|
|
4-aminobutanoate + Vanillin <=> vanillylamine + succinate_semialdehyde
|
2.6.1.119
vanillin aminotransferase
|
–
|
|
|
BRENDA:
BS455030
|
|
|
|
4-aminobutanoate <=> Propylamine + CO2
|
4.1.1.86
diaminobutyrate decarboxylase
|
–
|
|
|
BRENDA:
BS379035
|
|
|
|
N-(4-aminobutyryl)-4-aminobutyric_acid + H2O <=> 4-aminobutanoate + 4-aminobutanoate
|
3.5.1.46
6-aminohexanoate-oligomer exohydrolase
|
–
|
|
|
BRENDA:
BS116330
|
|
|
|
N-(6-aminohexanoyl)-4-aminobutyric_acid + H2O <=> 6-aminohexanoate + 4-aminobutanoate
|
3.5.1.46
6-aminohexanoate-oligomer exohydrolase
|
–
|
|
|
BRENDA:
BS116331
|
|
|
|
ATP + 4-aminobutanoate + CoA <=> ADP + phosphate + 4-aminobutanoyl-CoA
|
6.2.1.B11
|
–
|
|
|
BRENDA:
BS425947
|
|
|
|
ATP + L-glutamate + 4-aminobutanoate <=> ADP + phosphate + 4-(glutamylamino)_butanoate
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
|
|
BRENDA:
BS369123
|
|
|
|
ATP + gamma-Glu-L-Cys + 4-aminobutanoate <=> ADP + phosphate + gamma-glutamylcysteinyl-4-aminobutyrate
|
6.3.2.23
homoglutathione synthase
6.3.2.3
glutathione synthase
|
–
–
|
|
|
BRENDA:
BS363613
|
|
|
|
ATP + 4-aminobutanoate + [acyl-carrier_protein] <=> ADP + phosphate + 4-aminobutanoyl-S-[BtrI_acyl-carrier_protein]
|
6.2.1.39
[butirosin acyl-carrier protein]---L-glutamate ligase
|
–
|
|
|
BRENDA:
BS420309
|
|
|
|
ATP + L-glutamate + 4-aminobutanoate <=> ADP + phosphate + L-Glu-gamma-aminobutyrate
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
|
|
BRENDA:
BS369124
|
|
|
|
ATP + gamma-Glu-L-Cys + 4-aminobutanoate <=> ADP + phosphate + gamma-L-Glu-L-Cys-gamma-aminobutyric_acid
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379337
|
|
|
|
Nalpha-(gamma-aminobutryryl)-Arg + H2O <=> 4-aminobutanoate + L-arginine
|
3.4.13.4
Xaa-Arg dipeptidase
|
–
|
|
|
BRENDA:
BS382395
|
|
|
|
ATP + L-histidine + 4-aminobutanoate <=> AMP + phosphate + homocarnosine
|
6.3.2.11
carnosine synthase
|
–
|
|
|
BRENDA:
BS405
|
|
|
|
ATP + 4-aminobutanoate + tRNAMet <=> AMP + 4-aminobutyryl-tRNALys + diphosphate
|
6.1.1.6
lysine---tRNA ligase
|
–
|
|
|
BRENDA:
BS368919
|
|
|
|
L-histidine + ATP + 4-aminobutanoate <=> homocarnosine + AMP + diphosphate
|
6.3.2.11
carnosine synthase
|
–
|
|
|
SABIO-RK:
2031
|
|
|
|
4-aminobutanoate + (R)-pantoate + ATP <=> diphosphate + Pantoyl-gamma-aminobutyric_acid + AMP
|
6.3.2.1
pantoate---beta-alanine ligase (AMP-forming)
|
–
|
|
|
SABIO-RK:
7763
|
|